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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1304
http://purl.obolibrary.org/obo/NCIT_C1304
|
|---|---|
| Preferred Name | PEG-interleukin-2 |
| Definitions |
A complex of polyethylene glycol conjugated with human recombinant cytokine interleukin-2 (IL-2) with antineoplastic activity. PEG-interleukin-2 induces natural killer (NK) cell activity and the production of interferon-gamma (IFN-gamma), and enhances T cell-mediated cytotoxicity. Pegylation of IL-2 protects the cytokine from degradation. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A complex of polyethylene glycol conjugated with human recombinant cytokine interleukin-2 (IL-2) with antineoplastic activity. PEG-interleukin-2 induces natural killer (NK) cell activity and the production of interferon-gamma (IFN-gamma), and enhances T cell-mediated cytotoxicity. Pegylation of IL-2 protects the cytokine from degradation. (NCI04) |
|---|---|
| prefLabel | PEG-interleukin-2
|
| label | PEG-interleukin-2
|
| PDQ_Closed_Trial_Search_ID | 39577
|
| code | C1304
|
| prefixIRI | NCIT:C1304
|
| in_subset | |
| Preferred_Name | PEG-interleukin-2
|
| Maps_To | PEG-interleukin-2
|
| NCI_Drug_Dictionary_ID | 39577
|
| Legacy Concept Name | PEG-interleukin-2
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39577
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| UMLS_CUI | C0083036
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