loading...| Preferred Name |
Antisense Oligonucleotides |
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| Synonyms |
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|
| Definitions |
Antisense Oligonucleotides, short synthetic segments of DNA or RNA, designed with a sequence complimentary to a specific mRNA that target and bind with mRNA, causing inhibition of translation or overexpression of the protein encoded by the mRNA. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1291 |
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| ALT_DEFINITION |
Small pieces of DNA or RNA that can bind to specific molecules of RNA. This blocks the ability of the RNA to make a protein or work in other ways. Antisense agents may be used to block the production of proteins needed for cell growth. They are being studied in the treatment of several types of cancer. |
|
| code |
C1291 |
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| definition |
Antisense Oligonucleotides, short synthetic segments of DNA or RNA, designed with a sequence complimentary to a specific mRNA that target and bind with mRNA, causing inhibition of translation or overexpression of the protein encoded by the mRNA. |
|
| label |
Antisense Oligonucleotides |
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| Legacy Concept Name |
Antisense_Agent |
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| NCI_Drug_Dictionary_ID |
41871 |
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| PDQ_Closed_Trial_Search_ID |
41871 |
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| PDQ_Open_Trial_Search_ID |
41871 |
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| Preferred_Name |
Antisense Oligonucleotides |
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| prefixIRI |
NCIT:C1291 |
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| prefLabel |
Antisense Oligonucleotides |
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| Semantic_Type |
Nucleic Acid, Nucleoside, or Nucleotide Chemical Viewed Functionally |
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| UMLS_CUI |
C4018803 |
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| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://localhost/plosthes.2017-1#4916 | PLOSTHES | LOOM | |
| http://sbmi.uth.tmc.edu/ontology/ochv#C0079925 | OCHV | LOOM | |
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1291 | NCIT | LOOM | |
| http://purl.obolibrary.org/obo/MI_1192 | MI | LOOM |