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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1290
http://purl.obolibrary.org/obo/NCIT_C1290
|
|---|---|
| Preferred Name | Recombinant Macrophage Colony-Stimulating Factor |
| Definitions |
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous protein cytokine macrophage colony-stimulating factor (M-CSF). Synthesized endogenously by mesenchymal cells, M-CSF stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series and can reverse treatment-related neutropenias. Recombinant M-CSF may also enhance antigen presentation and activate antitumoral cytotoxic T-cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A recombinant therapeutic agent which is chemically identical to or similar to the endogenous protein cytokine macrophage colony-stimulating factor (M-CSF). Synthesized endogenously by mesenchymal cells, M-CSF stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series and can reverse treatment-related neutropenias. Recombinant M-CSF may also enhance antigen presentation and activate antitumoral cytotoxic T-cells. |
|---|---|
| prefLabel | Recombinant Macrophage Colony-Stimulating Factor
|
| label | Recombinant Macrophage Colony-Stimulating Factor
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| PDQ_Closed_Trial_Search_ID | 40240
|
| code | C1290
|
| prefixIRI | NCIT:C1290
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| in_subset | |
| Preferred_Name | Recombinant Macrophage Colony-Stimulating Factor
|
| Maps_To | Recombinant Macrophage Colony-Stimulating Factor
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| CAS_Registry | 81627-83-0
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| NCI_Drug_Dictionary_ID | 40240
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| Legacy Concept Name | Recombinant_Macrophage_Colony-Stimulating_Factor
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 40240
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| UMLS_CUI | C0079784
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| Delete | Subject | Author | Type | Created |
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