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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C128898
http://purl.obolibrary.org/obo/NCIT_C128898
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|---|---|
| Preferred Name | Multi-epitope Anti-folate Receptor Peptide Vaccine TPIV 200 |
| Definitions |
A peptide vaccine containing five immunogenic peptide epitopes of the human folate receptor 1 (FOLR1; FR-alpha), with potential immunomodulating and antineoplastic activities. Upon intradermal administration, multi-epitope anti-folate receptor peptide vaccine TPIV 200 may induce a cytotoxic T-lymphocyte (CTL) response against FR-alpha-overexpressing tumor cells. FR-alpha is a high-affinity folate-binding protein and a member of the folate receptor family; this receptor is overexpressed in various cancer cell types.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A peptide vaccine containing five immunogenic peptide epitopes of the human folate receptor 1 (FOLR1; FR-alpha), with potential immunomodulating and antineoplastic activities. Upon intradermal administration, multi-epitope anti-folate receptor peptide vaccine TPIV 200 may induce a cytotoxic T-lymphocyte (CTL) response against FR-alpha-overexpressing tumor cells. FR-alpha is a high-affinity folate-binding protein and a member of the folate receptor family; this receptor is overexpressed in various cancer cell types. |
|---|---|
| prefLabel | Multi-epitope Anti-folate Receptor Peptide Vaccine TPIV 200
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| label | Multi-epitope Anti-folate Receptor Peptide Vaccine TPIV 200
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| NCI_META_CUI | CL512164
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| PDQ_Closed_Trial_Search_ID | 782632
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| code | C128898
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| prefixIRI | NCIT:C128898
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| in_subset |
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| Display_Name | Multi-epitope Anti-folate Receptor Peptide Vaccine TPIV 200
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| Preferred_Name | Multi-epitope Anti-folate Receptor Peptide Vaccine TPIV 200
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| Contributing_Source | CTRP
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| Maps_To | Multi-epitope Anti-folate Receptor Peptide Vaccine TPIV 200
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| NCI_Drug_Dictionary_ID | 782632
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 782632
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| Semantic_Type | Pharmacologic Substance
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