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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1288
http://purl.obolibrary.org/obo/NCIT_C1288
|
|---|---|
| Preferred Name | Recombinant Granulocyte-Macrophage Colony-Stimulating Factor |
| Definitions |
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein cytokine growth factor granulocyte-macrophage colony stimulating factor (GM-CSF). Therapeutic GM-CSF induces the clonal expansion and differentiation of progenitor blood cells and stimulates the cytotoxicity of monocytes and neutrophils, thereby restoring immune function and host antitumor immune responses and stimulating engraftment of transplanted bone marrow tissue. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein cytokine growth factor granulocyte-macrophage colony stimulating factor (GM-CSF). Therapeutic GM-CSF induces the clonal expansion and differentiation of progenitor blood cells and stimulates the cytotoxicity of monocytes and neutrophils, thereby restoring immune function and host antitumor immune responses and stimulating engraftment of transplanted bone marrow tissue. (NCI04) |
|---|---|
| prefLabel | Recombinant Granulocyte-Macrophage Colony-Stimulating Factor
|
| label | Recombinant Granulocyte-Macrophage Colony-Stimulating Factor
|
| code | C1288
|
| Has_Target | |
| prefixIRI | NCIT:C1288
|
| in_subset | |
| Preferred_Name | Recombinant Granulocyte-Macrophage Colony-Stimulating Factor
|
| Maps_To | Recombinant Granulocyte-Macrophage Colony-Stimulating Factor
|
| CAS_Registry | 83869-56-1
|
| NSC Number |
613795
617589
622183
643496
|
| Legacy Concept Name | Therapeutic_Granulocyte-Macrophage_Colony-Stimulating_Factor
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
|
| UMLS_CUI | C0376563
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