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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Id | http://purl.obolibrary.org/obo/NCIT_C128346
http://purl.obolibrary.org/obo/NCIT_C128346
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|---|---|
| Preferred Name | Transmissible Spongiform Encephalopathy |
| Definitions |
A transmissible, infectious disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A transmissible, infectious disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal. |
|---|---|
| label |
Transmissible Spongiform Encephalopathy
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| prefLabel |
Transmissible Spongiform Encephalopathy
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| database_cross_reference |
IMDRF:E1905
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| in_subset | |
| Preferred_Name |
Transmissible Spongiform Encephalopathy
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| UMLS_CUI |
C0162534
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| prefixIRI |
NCIT:C128346
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| Contributing_Source |
FDA
NICHD
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| subClassOf | |
| code |
C128346
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| type | |
| ALT_DEFINITION |
A group of rare degenerative brain disorders associated with orions for example Creutzfeldt-Jakob disease (CJD) or Bovine Spongiform Encephalopathy (BSE).
A transmissible, infectious disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.
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| Semantic_Type |
Disease or Syndrome
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