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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C128280
http://purl.obolibrary.org/obo/NCIT_C128280
|
|---|---|
| Preferred Name | Selective Estrogen Receptor Degrader LSZ102 |
| Definitions |
An selective estrogen receptor (ER) degrader (SERD), with potential antineoplastic activity. Upon administration of LSZ102, this agent binds to the ER and induces the degradation of the receptor. This prevents ER activation and ER-mediated signaling, and inhibits the growth and survival of ER-expressing cancer cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An selective estrogen receptor (ER) degrader (SERD), with potential antineoplastic activity. Upon administration of LSZ102, this agent binds to the ER and induces the degradation of the receptor. This prevents ER activation and ER-mediated signaling, and inhibits the growth and survival of ER-expressing cancer cells. |
|---|---|
| prefLabel | Selective Estrogen Receptor Degrader LSZ102
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| label | Selective Estrogen Receptor Degrader LSZ102
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| NCI_META_CUI | CL507934
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| PDQ_Closed_Trial_Search_ID | 782046
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| code | C128280
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| Has_Target | |
| prefixIRI | NCIT:C128280
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| in_subset |
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| Display_Name | Selective Estrogen Receptor Degrader LSZ102
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| Preferred_Name | Selective Estrogen Receptor Degrader LSZ102
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| FDA_UNII_Code | 0Y175XGX4P
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Selective Estrogen Receptor Degrader LSZ102
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| CAS_Registry | 2135600-76-7
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| NCI_Drug_Dictionary_ID | 782046
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 782046
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| Delete | Subject | Author | Type | Created |
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