Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1267
http://purl.obolibrary.org/obo/NCIT_C1267
|
|---|---|
| Preferred Name | Triptorelin |
| Definitions |
A synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. (NCI04)
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. (NCI04) |
|---|---|
| prefLabel | Triptorelin
|
| label | Triptorelin
|
| Has_Salt_Form | |
| CHEBI_ID | CHEBI:63633
|
| PDQ_Closed_Trial_Search_ID | 42944
|
| code | C1267
|
| Has_Target | |
| prefixIRI | NCIT:C1267
|
| in_subset |
See more
See less
|
| Display_Name | Triptorelin
|
| Preferred_Name | Triptorelin
|
| FDA_UNII_Code | 9081Y98W2V
|
| Contributing_Source |
CTRP
FDA
|
| Chemical_Formula | C64H82N18O13
|
| Maps_To | Triptorelin
|
| CAS_Registry | 57773-63-4
|
| NCI_Drug_Dictionary_ID | 42944
|
| Legacy Concept Name | Triptorelin
|
| type | |
| ALT_DEFINITION | A drug that is used to treat advanced prostate cancer, and is being studied in the treatment of breast cancer. It belongs to the family of hormonal drugs called gonadotropin-releasing hormone analogs.
|
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 42944
|
| Accepted_Therapeutic_Use_For | Palliative treatment prostate carcinoma
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
|
| UMLS_CUI | C0077275
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |