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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C125900
http://purl.obolibrary.org/obo/NCIT_C125900
|
|---|---|
| Preferred Name | Anti-CA19-9 Monoclonal Antibody 5B1 |
| Definitions |
A human monoclonal antibody against the carbohydrate antigen sialyl-Lewis A (carbohydrate antigen 19-9; CA19-9), with potential antineoplastic activity. Upon administration, monoclonal antibody 5B1 binds to CA19-9 and kills CA19-9-expressing tumor cells, possibly through the induction of both complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC). CA19-9 is overexpressed on a number of different tumor cell types, and plays a key role in tumor cell survival and metastasis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A human monoclonal antibody against the carbohydrate antigen sialyl-Lewis A (carbohydrate antigen 19-9; CA19-9), with potential antineoplastic activity. Upon administration, monoclonal antibody 5B1 binds to CA19-9 and kills CA19-9-expressing tumor cells, possibly through the induction of both complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC). CA19-9 is overexpressed on a number of different tumor cell types, and plays a key role in tumor cell survival and metastasis. |
|---|---|
| prefLabel | Anti-CA19-9 Monoclonal Antibody 5B1
|
| label | Anti-CA19-9 Monoclonal Antibody 5B1
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| NCI_META_CUI | CL504549
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| PDQ_Closed_Trial_Search_ID | 778807
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| code | C125900
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| Has_Target | |
| prefixIRI | NCIT:C125900
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| in_subset |
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| Display_Name | Anti-CA19-9 Monoclonal Antibody 5B1
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| Preferred_Name | Anti-CA19-9 Monoclonal Antibody 5B1
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| FDA_UNII_Code | KEX1QY18OH
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Anti-CA19-9 Monoclonal Antibody 5B1
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| CAS_Registry | 2101410-19-7
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| NCI_Drug_Dictionary_ID | 778807
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 778807
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| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
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