Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C1256
http://purl.obolibrary.org/obo/NCIT_C1256
Preferred Name

Toremifene
Definitions
A nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This agent binds competitively to estrogen receptors, thereby interfering with estrogen activity. Toremifene also has intrinsic estrogenic properties, which are manifested according to tissue type or species. (NCI04)
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This agent binds competitively to estrogen receptors, thereby interfering with estrogen activity. Toremifene also has intrinsic estrogenic properties, which are manifested according to tissue type or species. (NCI04)
prefLabel
Toremifene
label
Toremifene
Has_Salt_Form
CHEBI_ID
CHEBI:9635
PDQ_Closed_Trial_Search_ID
41103
code
C1256
prefixIRI
NCIT:C1256
in_subset
Preferred_Name
Toremifene
FDA_UNII_Code
7NFE54O27T
Contributing_Source
FDA
Chemical_Formula
C26H28ClNO
Maps_To
Toremifene
CAS_Registry
89778-26-7
NCI_Drug_Dictionary_ID
41103
Legacy Concept Name
Toremifene
type
ALT_DEFINITION
An anticancer drug that belongs to the family of drugs called antiestrogens. Toremifene blocks the effect of the hormone estrogen in the body. It may help control some cancers from growing, and it may delay or reduce the risk of cancer recurrence.
Is_Value_For_GDC_Property
subClassOf
PDQ_Open_Trial_Search_ID
41103
Accepted_Therapeutic_Use_For
Breast cancer; Desmoid tumors
Semantic_Type
Organic Chemical
Pharmacologic Substance
UMLS_CUI
C0076836
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