Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C1250 http://purl.obolibrary.org/obo/NCIT_C1250
Preferred Name	Ormaplatin
Definitions	A platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity.
Type	http://www.w3.org/2002/07/owl#Class

definition	A platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity.
label	Ormaplatin
prefLabel	Ormaplatin
Legacy Concept Name	Ormaplatin
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Ormaplatin
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
Chemical_Formula	C6H14N2.4Cl.Pt
Maps_To	Ormaplatin
PDQ_Open_Trial_Search_ID	41211
UMLS_CUI	C0076329
FDA_UNII_Code	SFK1SGY8V1
prefixIRI	NCIT:C1250
NCI_Drug_Dictionary_ID	41211
Contributing_Source	FDA
subClassOf	http://purl.obolibrary.org/obo/NCIT_C1450
code	C1250
type	http://www.w3.org/2002/07/owl#Class
NSC Number	363812
PDQ_Closed_Trial_Search_ID	41211
Semantic_Type	Pharmacologic Substance Inorganic Chemical
CAS_Registry	62816-98-2

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