loading...| Preferred Name |
Thymus Gland |
|
| Synonyms |
|
|
| Definitions |
A bi-lobed organ surrounded by a connective tissue capsule. It is located in the upper anterior portion of the chest, behind the sternum. It is composed predominantly of lymphocytes and fewer epithelial cells. Connective tissue septa separate the lobes into lobules. The lobules contain an outer portion (cortical zone) which is rich in lymphocytes and an inner portion (medullary zone) which is rich in epithelial cells. It is an organ essential for the development of the immune system. Its function is the maturation of the progenitor lymphoid cells to thymocytes and subsequently to mature T-cells. It reaches its greatest weight at puberty and subsequently begins to involute. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C12433 |
|
| ALT_DEFINITION |
A primary lymphoid organ generally located in the mediastinum near the thoracic inlet and/or along lateral aspects of the neck. An organ that is part of the lymphatic system, in which T lymphocytes grow and multiply. The thymus is in the chest behind the breastbone. |
|
| code |
C12433 |
|
| Contributing_Source |
CDISC GDC PCDC |
|
| definition |
A bi-lobed organ surrounded by a connective tissue capsule. It is located in the upper anterior portion of the chest, behind the sternum. It is composed predominantly of lymphocytes and fewer epithelial cells. Connective tissue septa separate the lobes into lobules. The lobules contain an outer portion (cortical zone) which is rich in lymphocytes and an inner portion (medullary zone) which is rich in epithelial cells. It is an organ essential for the development of the immune system. Its function is the maturation of the progenitor lymphoid cells to thymocytes and subsequently to mature T-cells. It reaches its greatest weight at puberty and subsequently begins to involute. |
|
| Display_Name |
Thymus Gland |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C77529 http://purl.obolibrary.org/obo/NCIT_C77526 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/ncit#oncotree_slim http://purl.obolibrary.org/obo/NCIT_C179482 http://purl.obolibrary.org/obo/NCIT_C179483 http://purl.obolibrary.org/obo/NCIT_C179481 http://purl.obolibrary.org/obo/NCIT_C74456 http://purl.obolibrary.org/obo/NCIT_C179478 http://purl.obolibrary.org/obo/NCIT_C66830 |
|
| Is_Value_For_GDC_Property |
http://purl.obolibrary.org/obo/NCIT_C177570 http://purl.obolibrary.org/obo/NCIT_C156422 http://purl.obolibrary.org/obo/NCIT_C156421 http://purl.obolibrary.org/obo/NCIT_C70729 |
|
| label |
Thymus Gland |
|
| Legacy Concept Name |
Thymus_Gland |
|
| Maps_To |
Thymus |
|
| Preferred_Name |
Thymus Gland |
|
| prefixIRI |
NCIT:C12433 |
|
| prefLabel |
Thymus Gland |
|
| Semantic_Type |
Body Part, Organ, or Organ Component |
|
| UMLS_CUI |
C0040113 |
|
| subClassOf |