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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1237
http://purl.obolibrary.org/obo/NCIT_C1237
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|---|---|
| Preferred Name | Staurosporine |
| Definitions |
A cell permeable alkaloid isolated from Streptomyces staurosporeus exhibiting anti-cancer activity. Staurosporine is a potent, non-selective inhibitor of protein kinases, including protein kinase C. This agent induces apoptosis by an undetermined mechanism. (NCI)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A cell permeable alkaloid isolated from Streptomyces staurosporeus exhibiting anti-cancer activity. Staurosporine is a potent, non-selective inhibitor of protein kinases, including protein kinase C. This agent induces apoptosis by an undetermined mechanism. (NCI) |
|---|---|
| prefLabel | Staurosporine
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| label | Staurosporine
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| CHEBI_ID | CHEBI:15738
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| code | C1237
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| prefixIRI | NCIT:C1237
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| in_subset | |
| Preferred_Name | Staurosporine
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| FDA_UNII_Code | H88EPA0A3N
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| Contributing_Source | FDA
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| Chemical_Formula | C28H26N4O3
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| Maps_To | Staurosporine
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| CAS_Registry | 62996-74-1
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| NSC Number | 618487
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| Legacy Concept Name | Staurosporine
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| type | |
| ALT_DEFINITION | A drug that belongs to the family of drugs called alkaloids. It is being studied in the treatment of cancer.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0075193
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