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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1234
http://purl.obolibrary.org/obo/NCIT_C1234
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|---|---|
| Preferred Name | Spiroplatin |
| Definitions |
A synthetic derivative of cyclohexane sulfatoplatinum with antineoplastic properties. Spiroplatin induces DNA cross-links, thereby inhibiting DNA replication and RNA and protein synthesis. Similar to other platinum compounds, this agent has been shown to be mutagenic and carcinogenic. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic derivative of cyclohexane sulfatoplatinum with antineoplastic properties. Spiroplatin induces DNA cross-links, thereby inhibiting DNA replication and RNA and protein synthesis. Similar to other platinum compounds, this agent has been shown to be mutagenic and carcinogenic. (NCI04) |
|---|---|
| prefLabel | Spiroplatin
|
| label | Spiroplatin
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| PDQ_Closed_Trial_Search_ID | 39763
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| code | C1234
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| prefixIRI | NCIT:C1234
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| in_subset | |
| Preferred_Name | Spiroplatin
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| FDA_UNII_Code | H2V318W7LE
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| Contributing_Source | FDA
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| Chemical_Formula | C8H18N2.O4S.Pt
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| Maps_To | Spiroplatin
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| CAS_Registry | 74790-08-2
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| NSC Number | 311056
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| NCI_Drug_Dictionary_ID | 39763
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| Legacy Concept Name | Spiroplatin
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39763
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| Semantic_Type |
Pharmacologic Substance
Inorganic Chemical
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| UMLS_CUI | C0075022
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