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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C123378
http://purl.obolibrary.org/obo/NCIT_C123378
|
|---|---|
| Preferred Name | HPV-6-targeting Immunotherapeutic Vaccine INO-3106 |
| Definitions |
A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus subtype 6 (HPV-6), with potential immunostimulating and antineoplastic activities. Administered via intramuscular electroporation, HPV-6-targeting immunotherapeutic vaccine INO-3106 expresses the HPV-6 E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells that are expressing those proteins, resulting in tumor cell lysis. HPV-6 infections are associated with aerodigestive malignancies.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus subtype 6 (HPV-6), with potential immunostimulating and antineoplastic activities. Administered via intramuscular electroporation, HPV-6-targeting immunotherapeutic vaccine INO-3106 expresses the HPV-6 E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells that are expressing those proteins, resulting in tumor cell lysis. HPV-6 infections are associated with aerodigestive malignancies. |
|---|---|
| prefLabel | HPV-6-targeting Immunotherapeutic Vaccine INO-3106
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| label | HPV-6-targeting Immunotherapeutic Vaccine INO-3106
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| PDQ_Closed_Trial_Search_ID | 764841
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| code | C123378
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| Has_Target | |
| prefixIRI | NCIT:C123378
|
| in_subset |
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| Display_Name | HPV-6-targeting Immunotherapeutic Vaccine INO-3106
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| Preferred_Name | HPV-6-targeting Immunotherapeutic Vaccine INO-3106
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| Contributing_Source | CTRP
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| Maps_To | HPV-6-targeting Immunotherapeutic Vaccine INO-3106
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| NCI_Drug_Dictionary_ID | 764841
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 764841
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C4053632
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