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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C122834
http://purl.obolibrary.org/obo/NCIT_C122834
|
|---|---|
| Preferred Name | Selective Estrogen Receptor Degrader AZD9496 |
| Definitions |
An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon administration, SERD AZD9496 binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon administration, SERD AZD9496 binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells. |
|---|---|
| prefLabel | Selective Estrogen Receptor Degrader AZD9496
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| label | Selective Estrogen Receptor Degrader AZD9496
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| PDQ_Closed_Trial_Search_ID | 764993
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| code | C122834
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| Has_Target | |
| prefixIRI | NCIT:C122834
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| in_subset |
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| Display_Name | Selective Estrogen Receptor Degrader AZD9496
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| Preferred_Name | Selective Estrogen Receptor Degrader AZD9496
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| FDA_UNII_Code | DA9P7LN909
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Selective Estrogen Receptor Degrader AZD9496
|
| CAS_Registry | 1639042-08-2
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| NCI_Drug_Dictionary_ID | 764993
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 764993
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C4053676
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| Delete | Subject | Author | Type | Created |
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