Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C1218 http://purl.obolibrary.org/obo/NCIT_C1218
Preferred Name	Rhizoxin
Definitions	A macrocyclic lactone. Rhizoxin binds to tubulin and inhibits microtubule assembly, thereby inducing cytotoxicity. This agent also may inhibit endothelial cell-induced angiogenic activity, which may result in decreased tumor cell proliferation. (NCI04)
Type	http://www.w3.org/2002/07/owl#Class

definition	A macrocyclic lactone. Rhizoxin binds to tubulin and inhibits microtubule assembly, thereby inducing cytotoxicity. This agent also may inhibit endothelial cell-induced angiogenic activity, which may result in decreased tumor cell proliferation. (NCI04)
prefLabel	Rhizoxin
label	Rhizoxin
PDQ_Closed_Trial_Search_ID	41718
code	C1218
prefixIRI	NCIT:C1218
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Rhizoxin
FDA_UNII_Code	C1V1Y784E4
Contributing_Source	FDA
Maps_To	Rhizoxin
CAS_Registry	90996-54-6
NSC Number	332598
NCI_Drug_Dictionary_ID	41718
Legacy Concept Name	Rhizoxin
type	http://www.w3.org/2002/07/owl#Class
ALT_DEFINITION	A substance that is being studied in the treatment of cancer. It comes from a fungus and is similar to vinca alkaloid drugs. It belongs to the family of drugs called antimitotic agents.
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C67477
PDQ_Open_Trial_Search_ID	41718
Semantic_Type	Organic Chemical Pharmacologic Substance Antibiotic
UMLS_CUI	C0073184

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