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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1217
http://purl.obolibrary.org/obo/NCIT_C1217
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|---|---|
| Preferred Name | Retinyl Palmitate |
| Definitions |
A naturally-occurring phenyl analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. As the most common form of vitamin A taken for dietary supplementation, retinyl palmitate binds to and activates retinoid receptors, thereby inducing cell differentiation and decreasing cell proliferation. This agent also inhibits carcinogen-induced neoplastic transformation, induces apoptosis in some cancer cell types, and exhibits immunomodulatory properties. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A naturally-occurring phenyl analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. As the most common form of vitamin A taken for dietary supplementation, retinyl palmitate binds to and activates retinoid receptors, thereby inducing cell differentiation and decreasing cell proliferation. This agent also inhibits carcinogen-induced neoplastic transformation, induces apoptosis in some cancer cell types, and exhibits immunomodulatory properties. (NCI04) |
|---|---|
| prefLabel | Retinyl Palmitate
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| label | Retinyl Palmitate
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| CHEBI_ID | CHEBI:17616
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| code | C1217
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| prefixIRI | NCIT:C1217
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| in_subset | |
| Preferred_Name | Retinyl Palmitate
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| FDA_UNII_Code | 1D1K0N0VVC
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| Contributing_Source | FDA
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| Chemical_Formula | C36H60O2
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| Maps_To | Retinyl Palmitate
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| CAS_Registry | 79-81-2
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| Legacy Concept Name | Retinyl_Palmitate
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| type | |
| ALT_DEFINITION | A drug being studied in cancer prevention. It belongs to the family of drugs called retinoids.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| Accepted_Therapeutic_Use_For | Dietary supplement; vitamin A deficiency; reduction in falciparum malaria episodes in children older than 12 months old; acne; diminishing malignant cell growth; enhancing the immune system; reduction in mortality of HIV-infected children
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0073115
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| Delete | Subject | Author | Type | Created |
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| No notes to display |