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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C119759
http://purl.obolibrary.org/obo/NCIT_C119759
|
|---|---|
| Preferred Name | Allogeneic Cellular Vaccine 1650-G |
| Definitions |
A pluripotent, allogeneic, tumor cell vaccine composed of irradiated tumor cells from the non-small cell lung cancer (NSCLC) cell line 1650 and the immunoadjuvant recombinant granulocyte-macrophage colony stimulating factor (GM-CSF) (1650-G), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic cellular vaccine 1650-G may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against tumor-associated antigens (TAAs) expressed on NSCLC cells. GM-CSF potentiates the antitumor immune response. The 1650 cell line is used as a source for TAAs.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A pluripotent, allogeneic, tumor cell vaccine composed of irradiated tumor cells from the non-small cell lung cancer (NSCLC) cell line 1650 and the immunoadjuvant recombinant granulocyte-macrophage colony stimulating factor (GM-CSF) (1650-G), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic cellular vaccine 1650-G may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against tumor-associated antigens (TAAs) expressed on NSCLC cells. GM-CSF potentiates the antitumor immune response. The 1650 cell line is used as a source for TAAs. |
|---|---|
| prefLabel | Allogeneic Cellular Vaccine 1650-G
|
| label | Allogeneic Cellular Vaccine 1650-G
|
| code | C119759
|
| prefixIRI | NCIT:C119759
|
| in_subset | |
| Display_Name | Allogeneic Cellular Vaccine 1650-G
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| Preferred_Name | Allogeneic Cellular Vaccine 1650-G
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| Contributing_Source | CTRP
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| Maps_To | Allogeneic Cellular Vaccine 1650-G
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
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| UMLS_CUI | C3896934
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