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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C118648
http://purl.obolibrary.org/obo/NCIT_C118648
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|---|---|
| Preferred Name | Nanoparticle-based Paclitaxel Suspension |
| Definitions |
A nanoparticle-based suspension containing the water-insoluble taxane paclitaxel, with potential antineoplastic activity. Upon intraperitoneal administration, paclitaxel binds to tubulin and inhibits the disassembly of microtubules, which leads to the inhibition of cell division. The nanoparticle-based formulation is devoid of toxic solvents, such as cremophor; therefore, this agent has fewer side effects than the standard, solvent-based paclitaxel formulation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A nanoparticle-based suspension containing the water-insoluble taxane paclitaxel, with potential antineoplastic activity. Upon intraperitoneal administration, paclitaxel binds to tubulin and inhibits the disassembly of microtubules, which leads to the inhibition of cell division. The nanoparticle-based formulation is devoid of toxic solvents, such as cremophor; therefore, this agent has fewer side effects than the standard, solvent-based paclitaxel formulation. |
|---|---|
| prefLabel | Nanoparticle-based Paclitaxel Suspension
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| label | Nanoparticle-based Paclitaxel Suspension
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| code | C118648
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| prefixIRI | NCIT:C118648
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| in_subset | |
| Display_Name | Nanoparticle-based Paclitaxel Suspension
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| Preferred_Name | Nanoparticle-based Paclitaxel Suspension
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| Contributing_Source | CTRP
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| Maps_To | Nanoparticle-based Paclitaxel Suspension
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C3898158
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