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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C118445
http://purl.obolibrary.org/obo/NCIT_C118445
|
|---|---|
| Preferred Name | Mycobacterium tuberculosis Arabinomannan Z-100 |
| Definitions |
An extract from Mycobacterium tuberculosis (M. tuberculosis) containing the polysaccharide arabinomannan, with potential immunostimulating activity. Upon administration of M. tuberculosis arabinomannan Z-100, this agent may activate the immune system by increasing the expression of various cytokines, such as interferon-gamma (IFNg) and interleukin-12. This inhibits the activity of suppressor T-cells, increases T helper 1 cell (Th1) activity and may restore the balance between Th1/Th2 cells. Additionally, Z-100 may inhibit metastasis and tumor cell proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An extract from Mycobacterium tuberculosis (M. tuberculosis) containing the polysaccharide arabinomannan, with potential immunostimulating activity. Upon administration of M. tuberculosis arabinomannan Z-100, this agent may activate the immune system by increasing the expression of various cytokines, such as interferon-gamma (IFNg) and interleukin-12. This inhibits the activity of suppressor T-cells, increases T helper 1 cell (Th1) activity and may restore the balance between Th1/Th2 cells. Additionally, Z-100 may inhibit metastasis and tumor cell proliferation. |
|---|---|
| prefLabel | Mycobacterium tuberculosis Arabinomannan Z-100
|
| label | Mycobacterium tuberculosis Arabinomannan Z-100
|
| PDQ_Closed_Trial_Search_ID | 764997
|
| code | C118445
|
| prefixIRI | NCIT:C118445
|
| in_subset | |
| Preferred_Name | Mycobacterium tuberculosis Arabinomannan Z-100
|
| FDA_UNII_Code | GE82Y78JTT
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| Contributing_Source | FDA
|
| Maps_To | Mycobacterium tuberculosis Arabinomannan Z-100
|
| NCI_Drug_Dictionary_ID | 764997
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 764997
|
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0149256
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