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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C118362
http://purl.obolibrary.org/obo/NCIT_C118362
|
|---|---|
| Preferred Name | Anti-MUC1 Monoclonal Antibody BTH1704 |
| Definitions |
A monoclonal antibody against the tumor associated antigen (TAA) mucin-1 (MUC1), with potential antineoplastic activity. Upon administration, anti-MUC1 monoclonal antibody BTH1704 targets and binds to MUC1 expressed on the surface of tumor cells, which can potentially activate the immune system to induce an antibody-dependent cellular cytotoxicity (ADCC) against MUC1-expressing tumor cells. MUC1, a glycoprotein overexpressed on the surface of a variety of cancer cells, plays a key role in tumor cell survival and proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A monoclonal antibody against the tumor associated antigen (TAA) mucin-1 (MUC1), with potential antineoplastic activity. Upon administration, anti-MUC1 monoclonal antibody BTH1704 targets and binds to MUC1 expressed on the surface of tumor cells, which can potentially activate the immune system to induce an antibody-dependent cellular cytotoxicity (ADCC) against MUC1-expressing tumor cells. MUC1, a glycoprotein overexpressed on the surface of a variety of cancer cells, plays a key role in tumor cell survival and proliferation. |
|---|---|
| prefLabel | Anti-MUC1 Monoclonal Antibody BTH1704
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| label | Anti-MUC1 Monoclonal Antibody BTH1704
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| PDQ_Closed_Trial_Search_ID | 764610
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| code | C118362
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| prefixIRI | NCIT:C118362
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| in_subset | |
| Preferred_Name | Anti-MUC1 Monoclonal Antibody BTH1704
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| Maps_To | Anti-MUC1 Monoclonal Antibody BTH1704
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| NCI_Drug_Dictionary_ID | 764610
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 764610
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C3896895
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