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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Nilutamide | |
| Synonyms |
|
|
| Definitions |
A synthetic, nonsteroidal agent with antiandrogenic properties. Nilutamide preferentially binds to androgen receptors and blocks androgen receptor activation by testosterone and other androgens; this agent may inhibit androgen-dependent growth of normal and neoplastic prostate cells. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1173 |
|
| Accepted_Therapeutic_Use_For |
Prostate cancer
|
|
| ALT_DEFINITION |
A drug that blocks the effects of male hormones in the body. It is a type of antiandrogen.
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|
| CAS_Registry |
63612-50-0
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|
| CHEBI_ID |
CHEBI:7573
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|
| Chemical_Formula |
C12H10F3N3O4
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|
| code |
C1173
|
|
| Contributing_Source |
CTRP FDA
|
|
| definition |
A synthetic, nonsteroidal agent with antiandrogenic properties. Nilutamide preferentially binds to androgen receptors and blocks androgen receptor activation by testosterone and other androgens; this agent may inhibit androgen-dependent growth of normal and neoplastic prostate cells. (NCI04)
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|
| Display_Name |
Nilutamide
|
|
| FDA_UNII_Code |
51G6I8B902
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|
| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 |
|
| Is_Value_For_GDC_Property | ||
| label |
Nilutamide
|
|
| Legacy Concept Name |
Nilutamide
|
|
| Maps_To |
Nilutamide
|
|
| NCI_Drug_Dictionary_ID |
40450
|
|
| NSC Number |
684588
|
|
| PDQ_Closed_Trial_Search_ID |
40450
|
|
| PDQ_Open_Trial_Search_ID |
40450
|
|
| Preferred_Name |
Nilutamide
|
|
| prefixIRI |
NCIT:C1173
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|
| prefLabel |
Nilutamide
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0722107
|
|
| subClassOf |
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