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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C116737
http://purl.obolibrary.org/obo/NCIT_C116737
|
|---|---|
| Preferred Name | Anti-CD33 Monoclonal Antibody BI 836858 |
| Definitions |
An engineered, fully human, immunoglobulin (Ig) G1 anti-CD33 monoclonal antibody, with potential antineoplastic activity. Upon administration, anti-CD33 monoclonal antibody BI 836858 induces an antibody-dependent cellular cytotoxicity (ADCC) against CD33-expressing tumor cells, leading to cell death. CD33, a cell surface antigen expressed on normal non-pluripotent hematopoietic stem cells, is overexpressed on myeloid leukemia cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An engineered, fully human, immunoglobulin (Ig) G1 anti-CD33 monoclonal antibody, with potential antineoplastic activity. Upon administration, anti-CD33 monoclonal antibody BI 836858 induces an antibody-dependent cellular cytotoxicity (ADCC) against CD33-expressing tumor cells, leading to cell death. CD33, a cell surface antigen expressed on normal non-pluripotent hematopoietic stem cells, is overexpressed on myeloid leukemia cells. |
|---|---|
| prefLabel | Anti-CD33 Monoclonal Antibody BI 836858
|
| label | Anti-CD33 Monoclonal Antibody BI 836858
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| NCI_META_CUI | CL446627
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| PDQ_Closed_Trial_Search_ID | 737148
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| code | C116737
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| Has_Target | |
| prefixIRI | NCIT:C116737
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| in_subset |
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| Display_Name | Anti-CD33 Monoclonal Antibody BI 836858
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| Preferred_Name | Anti-CD33 Monoclonal Antibody BI 836858
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| FDA_UNII_Code | JA7I0QFJ17
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Anti-CD33 Monoclonal Antibody BI 836858
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| CAS_Registry | 2206770-25-2
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| NCI_Drug_Dictionary_ID | 737148
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 737148
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
Immunologic Factor
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| Delete | Subject | Author | Type | Created |
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