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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C116331
http://purl.obolibrary.org/obo/NCIT_C116331
|
|---|---|
| Preferred Name | Synthetic Glioblastoma Tumor-associated Peptides Vaccine Therapy APVAC1 |
| Definitions |
A personalized peptide-based cancer vaccine comprised of five to ten peptides associated with glioblastoma (GB), with potential immunomodulating and antineoplastic activities. Vaccination with synthetic GB tumor-associated peptides vaccine therapy APVAC1 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the tumor associated peptides, and results in decreased GB growth. The peptides are derived from a glioma actively personalized vaccine consortium (GAPVAC) warehouse and are specifically selected based on the patient's expression of tumor-associated antigens.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A personalized peptide-based cancer vaccine comprised of five to ten peptides associated with glioblastoma (GB), with potential immunomodulating and antineoplastic activities. Vaccination with synthetic GB tumor-associated peptides vaccine therapy APVAC1 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the tumor associated peptides, and results in decreased GB growth. The peptides are derived from a glioma actively personalized vaccine consortium (GAPVAC) warehouse and are specifically selected based on the patient's expression of tumor-associated antigens. |
|---|---|
| prefLabel | Synthetic Glioblastoma Tumor-associated Peptides Vaccine Therapy APVAC1
|
| label | Synthetic Glioblastoma Tumor-associated Peptides Vaccine Therapy APVAC1
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| NCI_META_CUI | CL473665
|
| PDQ_Closed_Trial_Search_ID | 761678
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| code | C116331
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| prefixIRI | NCIT:C116331
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| in_subset | |
| Preferred_Name | Synthetic Glioblastoma Tumor-associated Peptides Vaccine Therapy APVAC1
|
| Maps_To | Synthetic Glioblastoma Tumor-associated Peptides Vaccine Therapy APVAC1
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| NCI_Drug_Dictionary_ID | 761678
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 761678
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| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
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