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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1163
http://purl.obolibrary.org/obo/NCIT_C1163
|
|---|---|
| Preferred Name | N-Methylformamide |
| Definitions |
A water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells. (NCI04) |
|---|---|
| prefLabel | N-Methylformamide
|
| label | N-Methylformamide
|
| CHEBI_ID | CHEBI:7438
|
| PDQ_Closed_Trial_Search_ID | 39511
|
| code | C1163
|
| prefixIRI | NCIT:C1163
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| in_subset | |
| Preferred_Name | N-Methylformamide
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| FDA_UNII_Code | XPE4G7Y986
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| Contributing_Source | FDA
|
| Chemical_Formula | C2H5NO
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| Maps_To | N-Methylformamide
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| CAS_Registry | 123-39-7
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| NSC Number | 3051
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| NCI_Drug_Dictionary_ID | 39511
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| Legacy Concept Name | N-Methylformamide
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39511
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0066373
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| Delete | Subject | Author | Type | Created |
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