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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1154
http://purl.obolibrary.org/obo/NCIT_C1154
|
|---|---|
| Preferred Name | Carbendazim |
| Definitions |
A broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspecified site on tubulin and suppresses microtubule assembly dynamic. This results in cell cycle arrest at the G2/M phase and an induction of apoptosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspecified site on tubulin and suppresses microtubule assembly dynamic. This results in cell cycle arrest at the G2/M phase and an induction of apoptosis. |
|---|---|
| prefLabel | Carbendazim
|
| label | Carbendazim
|
| PDQ_Closed_Trial_Search_ID | 43319
|
| code | C1154
|
| prefixIRI | NCIT:C1154
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| in_subset | |
| Preferred_Name | Carbendazim
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| FDA_UNII_Code | H75J14AA89
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| Contributing_Source | FDA
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| Chemical_Formula | C9H9N3O2
|
| Maps_To | Carbendazim
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| CAS_Registry | 10605-21-7
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| NSC Number | 109874
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| NCI_Drug_Dictionary_ID | 43319
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| Legacy Concept Name | Carbendazim
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| type | |
| ALT_DEFINITION | An anticancer drug that belongs to the family of drugs called antifungal agents.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 43319
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0065839
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| Delete | Subject | Author | Type | Created |
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