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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C114496
http://purl.obolibrary.org/obo/NCIT_C114496
|
|---|---|
| Preferred Name | Glioma-associated Peptide-loaded Dendritic Cell Vaccine SL-701 |
| Definitions |
A cell-based cancer vaccine comprised of dendritic cells (DCs) pulsed with various, synthetic glioma-associated antigen (GAA) peptides, with potential antineoplastic activity. Upon subcutaneous administration, the glioma-associated peptide-loaded DC vaccine SL-701 exposes the immune system to various GAA peptides. This may stimulate both anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against the GAA-expressing glioma cells, which may result in tumor cell lysis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A cell-based cancer vaccine comprised of dendritic cells (DCs) pulsed with various, synthetic glioma-associated antigen (GAA) peptides, with potential antineoplastic activity. Upon subcutaneous administration, the glioma-associated peptide-loaded DC vaccine SL-701 exposes the immune system to various GAA peptides. This may stimulate both anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against the GAA-expressing glioma cells, which may result in tumor cell lysis. |
|---|---|
| prefLabel | Glioma-associated Peptide-loaded Dendritic Cell Vaccine SL-701
|
| label | Glioma-associated Peptide-loaded Dendritic Cell Vaccine SL-701
|
| NCI_META_CUI | CL472322
|
| PDQ_Closed_Trial_Search_ID | 759093
|
| code | C114496
|
| prefixIRI | NCIT:C114496
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| in_subset | |
| Preferred_Name | Glioma-associated Peptide-loaded Dendritic Cell Vaccine SL-701
|
| Maps_To | Glioma-associated Peptide-loaded Dendritic Cell Vaccine SL-701
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| NCI_Drug_Dictionary_ID | 759093
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 759093
|
| Semantic_Type |
Pharmacologic Substance
Cell
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