loading...| Preferred Name |
Autoimmune Regulator |
|
| Synonyms |
|
|
| Definitions |
Autoimmune regulator (545 aa, ~58 kDa) is encoded by the human AIRE gene. This protein is involved in both the activation of gene transcription and the inhibition of autoimmunity. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C114321 |
|
| code |
C114321 |
|
| Contributing_Source |
CTRP |
|
| definition |
Autoimmune regulator (545 aa, ~58 kDa) is encoded by the human AIRE gene. This protein is involved in both the activation of gene transcription and the inhibition of autoimmunity. |
|
| DesignNote |
Autoimmune regulator binds to DNA as a dimer or a tetramer by associating with G-doublets in an A/T-rich environment; the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. (UniProt) |
|
| Display_Name |
Autoimmune Regulator |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
|
| label |
Autoimmune Regulator |
|
| OMIM_Number |
607358 |
|
| Preferred_Name |
Autoimmune Regulator |
|
| prefixIRI |
NCIT:C114321 |
|
| prefLabel |
Autoimmune Regulator |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein |
|
| Swiss_Prot |
O43918 |
|
| UMLS_CUI |
C1741275 |
|
| subClassOf |