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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C11252
http://purl.obolibrary.org/obo/NCIT_C11252
|
|---|---|
| Preferred Name | Eniluracil/5-FU Combination Tablet |
| Definitions |
A combination tablet of ethynyluracil and fluorouracil. Fluorouracil is an antimetabolite fluoropyrimidine analog of the nucleoside pyrimidine with antineoplastic activity. Ethynyluracil is an orally-active fluoropyrimidine analog that inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil in the liver. This may lead to an increase in the bioavailability and, effectiveness of fluorouracil.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A combination tablet of ethynyluracil and fluorouracil. Fluorouracil is an antimetabolite fluoropyrimidine analog of the nucleoside pyrimidine with antineoplastic activity. Ethynyluracil is an orally-active fluoropyrimidine analog that inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil in the liver. This may lead to an increase in the bioavailability and, effectiveness of fluorouracil. |
|---|---|
| prefLabel | Eniluracil/5-FU Combination Tablet
|
| label | Eniluracil/5-FU Combination Tablet
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| PDQ_Closed_Trial_Search_ID | 42618
|
| code | C11252
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| Has_Target | |
| prefixIRI | NCIT:C11252
|
| in_subset | |
| Preferred_Name | Eniluracil/5-FU Combination Tablet
|
| Maps_To | Eniluracil/5-FU Combination Tablet
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| NSC Number | 710026
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| NCI_Drug_Dictionary_ID | 42618
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| Legacy Concept Name | Ethynyluracil_Fluorouracil
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 42618
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0393027
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| Delete | Subject | Author | Type | Created |
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