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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1119
http://purl.obolibrary.org/obo/NCIT_C1119
|
|---|---|
| Preferred Name | Ondansetron |
| Definitions |
A carbazole derivative with antiemetic activity. As a selective serotonin receptor antagonist, ondansetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. (NCI04)
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A carbazole derivative with antiemetic activity. As a selective serotonin receptor antagonist, ondansetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. (NCI04) |
|---|---|
| prefLabel | Ondansetron
|
| label | Ondansetron
|
| Has_Salt_Form | |
| PDQ_Closed_Trial_Search_ID | 40693
|
| code | C1119
|
| Has_Target | |
| prefixIRI | NCIT:C1119
|
| in_subset | |
| Display_Name | Ondansetron
|
| Preferred_Name | Ondansetron
|
| FDA_UNII_Code | 4AF302ESOS
|
| Contributing_Source |
CTRP
FDA
|
| Chemical_Formula | C18H19N3O
|
| CAS_Registry |
116002-70-1
99614-02-5
|
| NCI_Drug_Dictionary_ID | 40693
|
| Legacy Concept Name | Ondansetron
|
| type | |
| ALT_DEFINITION | The active ingredient in a drug used to treat nausea and vomiting caused by cancer treatment. Ondansetron is a type of serotonin receptor antagonist and a type of antiemetic.
|
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 40693
|
| Accepted_Therapeutic_Use_For | Nausea and vomiting prophylaxis, chemotherapy-induced and postoperative
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| UMLS_CUI | C0061851
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| Delete | Subject | Author | Type | Created |
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