Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C1118
http://purl.obolibrary.org/obo/NCIT_C1118
Preferred Name

Gossypol Acetic Acid
Definitions
The naturally occurring acetic acid form of gossypol, and an orally available polyphenolic aldehyde derived mostly from cottonseed with potential antineoplastic activity. The biologic activities of gossypol acetic acid are similar to those of gossypol and include suppression of DNA replication, inhibition of tumor cell proliferation, and male contraceptive effects. (NCI04)
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

The naturally occurring acetic acid form of gossypol, and an orally available polyphenolic aldehyde derived mostly from cottonseed with potential antineoplastic activity. The biologic activities of gossypol acetic acid are similar to those of gossypol and include suppression of DNA replication, inhibition of tumor cell proliferation, and male contraceptive effects. (NCI04)
prefLabel
Gossypol Acetic Acid
label
Gossypol Acetic Acid
code
C1118
prefixIRI
NCIT:C1118
in_subset
Preferred_Name
Gossypol Acetic Acid
FDA_UNII_Code
S7RL72610R
Contributing_Source
FDA
Chemical_Formula
C30H30O8.C2H4O2
Maps_To
Gossypol Acetic Acid
CAS_Registry
12542-36-8
Legacy Concept Name
Gossypol_Acetic_Acid
Has_Free_Acid_Or_Base_Form
type
ALT_DEFINITION
A substance being studied in the treatment of several types of cancer. It is a form of a chemical taken from the seed of the cotton plant (Gossypium). It blocks the growth of cells and may kill cancer cells. Gossypol acetic acid may also act as a male contraceptive (form of birth control).
Is_Value_For_GDC_Property
subClassOf
Semantic_Type
Organic Chemical
Pharmacologic Substance
UMLS_CUI
C0061824
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