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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C111574
http://purl.obolibrary.org/obo/NCIT_C111574
|
|---|---|
| Preferred Name | mRNA-derived Lung Cancer Vaccine BI 1361849 |
| Definitions |
A non-small cell lung cancer (NSCLC) vaccine containing six modified mRNAs, which encode six different NSCLC associated antigens, with potential antitumor and immunomodulatory activities. Upon intradermal administration, mRNA-derived lung cancer vaccine BI 1361849 may stimulate the immune system to mount both humoral and cellular responses against NSCLC cells. The six tumor-associated antigens (TAAs) encoded by these mRNAs are frequently expressed by NSCLC cells and are minimally expressed or absent in normal, healthy cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A non-small cell lung cancer (NSCLC) vaccine containing six modified mRNAs, which encode six different NSCLC associated antigens, with potential antitumor and immunomodulatory activities. Upon intradermal administration, mRNA-derived lung cancer vaccine BI 1361849 may stimulate the immune system to mount both humoral and cellular responses against NSCLC cells. The six tumor-associated antigens (TAAs) encoded by these mRNAs are frequently expressed by NSCLC cells and are minimally expressed or absent in normal, healthy cells. |
|---|---|
| prefLabel | mRNA-derived Lung Cancer Vaccine BI 1361849
|
| label | mRNA-derived Lung Cancer Vaccine BI 1361849
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| NCI_META_CUI | CL453982
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| PDQ_Closed_Trial_Search_ID | 752248
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| code | C111574
|
| prefixIRI | NCIT:C111574
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| in_subset | |
| Preferred_Name | mRNA-derived Lung Cancer Vaccine BI 1361849
|
| Maps_To | mRNA-derived Lung Cancer Vaccine BI 1361849
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| NCI_Drug_Dictionary_ID | 752248
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 752248
|
| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
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