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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1092
http://purl.obolibrary.org/obo/NCIT_C1092
|
|---|---|
| Preferred Name | Etanidazole |
| Definitions |
A 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant regions of primary tumors or metastases. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant regions of primary tumors or metastases. (NCI04) |
|---|---|
| prefLabel | Etanidazole
|
| label | Etanidazole
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| PDQ_Closed_Trial_Search_ID | 39446
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| code | C1092
|
| Has_Target | |
| prefixIRI | NCIT:C1092
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| in_subset |
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| Display_Name | Etanidazole
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| Preferred_Name | Etanidazole
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| FDA_UNII_Code | 30DKA3Q1HL
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| Contributing_Source |
CTRP
FDA
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| Chemical_Formula | C7H10N4O4
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| Maps_To | Etanidazole
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| CAS_Registry | 22668-01-5
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| NSC Number | 301467
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| NCI_Drug_Dictionary_ID | 39446
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| Legacy Concept Name | Etanidazole
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| type | |
| ALT_DEFINITION | A drug that increases the effectiveness of radiation therapy.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39446
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0059682
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| Delete | Subject | Author | Type | Created |
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