Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C1080 http://purl.obolibrary.org/obo/NCIT_C1080
Preferred Name	Elsamitrucin
Definitions	An heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits topoisomerase I and II, resulting in single-strand breaks and inhibition of DNA replication. (NCI04)
Type	http://www.w3.org/2002/07/owl#Class

definition	An heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits topoisomerase I and II, resulting in single-strand breaks and inhibition of DNA replication. (NCI04)
label	Elsamitrucin
prefLabel	Elsamitrucin
Legacy Concept Name	Elsamitrucin
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Elsamitrucin
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
Chemical_Formula	C33H35NO13
Maps_To	Elsamitrucin
PDQ_Open_Trial_Search_ID	41409
UMLS_CUI	C0059041
FDA_UNII_Code	ZTV0FOB6NU
prefixIRI	NCIT:C1080
NCI_Drug_Dictionary_ID	41409
Contributing_Source	FDA
subClassOf	http://purl.obolibrary.org/obo/NCIT_C259 http://purl.obolibrary.org/obo/NCIT_C1968
code	C1080
type	http://www.w3.org/2002/07/owl#Class
PDQ_Closed_Trial_Search_ID	41409
Semantic_Type	Organic Chemical Pharmacologic Substance
CAS_Registry	97068-30-9

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