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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1078
http://purl.obolibrary.org/obo/NCIT_C1078
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|---|---|
| Preferred Name | Brequinar Sodium |
| Definitions |
The sodium salt form of Brequinar. Brequinar inhibits the enzyme dihydroorotate dehydrogenase, thereby blocking de novo pyrimidine biosynthesis. This agent may also enhance the in vivo antitumor effect of antineoplastic agents such as 5-FU. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The sodium salt form of Brequinar. Brequinar inhibits the enzyme dihydroorotate dehydrogenase, thereby blocking de novo pyrimidine biosynthesis. This agent may also enhance the in vivo antitumor effect of antineoplastic agents such as 5-FU. (NCI04) |
|---|---|
| prefLabel | Brequinar Sodium
|
| label | Brequinar Sodium
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| code | C1078
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| prefixIRI | NCIT:C1078
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| in_subset |
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| Preferred_Name | Brequinar Sodium
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| FDA_UNII_Code | 49EEF6HRUS
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| Contributing_Source | FDA
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| Chemical_Formula | C23H14F2NO2.Na
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| Maps_To | Brequinar Sodium
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| CAS_Registry | 96201-88-6
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| NSC Number | 368390
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| Legacy Concept Name | Brequinar_Sodium
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| Has_Free_Acid_Or_Base_Form | |
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0058809
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