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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1073
http://purl.obolibrary.org/obo/NCIT_C1073
|
|---|---|
| Preferred Name | Dimethylmyleran |
| Definitions |
An aliphatic analogue of busulfan with potential antineoplastic activity. As an alkylating agent, dimethylbusulfan induces neutropenia and has been shown to exhibit antitumor effects in some animal models. Alkylating agents exert cytotoxic and chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An aliphatic analogue of busulfan with potential antineoplastic activity. As an alkylating agent, dimethylbusulfan induces neutropenia and has been shown to exhibit antitumor effects in some animal models. Alkylating agents exert cytotoxic and chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division. (NCI04) |
|---|---|
| prefLabel | Dimethylmyleran
|
| label | Dimethylmyleran
|
| PDQ_Closed_Trial_Search_ID | 39221
|
| code | C1073
|
| prefixIRI | NCIT:C1073
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| in_subset | |
| Preferred_Name | Dimethylmyleran
|
| Maps_To | Dimethylmyleran
|
| CAS_Registry | 55-93-6
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| NSC Number |
180541
180542
180543
23890
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| NCI_Drug_Dictionary_ID | 39221
|
| Legacy Concept Name | Dimethylbusulfan
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39221
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0058272
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