Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C1058
http://purl.obolibrary.org/obo/NCIT_C1058
Preferred Name

Cortisone Acetate
Definitions
The acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

The acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.
prefLabel
Cortisone Acetate
label
Cortisone Acetate
code
C1058
prefixIRI
NCIT:C1058
in_subset
Preferred_Name
Cortisone Acetate
FDA_UNII_Code
883WKN7W8X
Contributing_Source
FDA
Chemical_Formula
C23H30O6
Maps_To
Cortisone Acetate
CAS_Registry
50-04-4
NSC Number
49420
Legacy Concept Name
Cortisone_Acetate
type
Is_Value_For_GDC_Property
subClassOf
Semantic_Type
Organic Chemical
Pharmacologic Substance
UMLS_CUI
C0056391
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