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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C104803
http://purl.obolibrary.org/obo/NCIT_C104803
|
|---|---|
| Preferred Name | Protein Kinase C Iota Type |
| Definitions |
Protein kinase C iota type (596 aa, ~68 kDa) is encoded by the human PRKCI gene. This protein plays a role in serine/threonine phosphorylation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Protein kinase C iota type (596 aa, ~68 kDa) is encoded by the human PRKCI gene. This protein plays a role in serine/threonine phosphorylation. |
|---|---|
| prefLabel | Protein Kinase C Iota Type
|
| label | Protein Kinase C Iota Type
|
| code | C104803
|
| prefixIRI | NCIT:C104803
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| OMIM_Number | 600539
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| in_subset | |
| Display_Name | Protein Kinase C Iota Type
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| Preferred_Name | Protein Kinase C Iota Type
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| Contributing_Source | CTRP
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| Swiss_Prot | P41743
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| DesignNote | Protein kinase C iota type is an atypical PKC, meaning that the kinase activity is independent of calcium, phosphatidylserine, phorbol esters or diacylglycerol. (UniProt)
Protein kinase C iota type is necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and protects leukemia cells against drug-induced apoptosis. (EntrezGene and UniProt)
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
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| UMLS_CUI | C1568202
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