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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1038
http://purl.obolibrary.org/obo/NCIT_C1038
|
|---|---|
| Preferred Name | Carbogen |
| Definitions |
An inhalant consisting of hyperoxic gas (95%-98% oxygen and 2%-5% carbon dioxide) with radiosensitizing properties. Inhaled carbogen reduces diffusion-limited tumor hypoxia, increasing tumor radiosensitivity due to the increased availability of molecular oxygen for cytotoxic radiation-induced oxygen free radical production. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An inhalant consisting of hyperoxic gas (95%-98% oxygen and 2%-5% carbon dioxide) with radiosensitizing properties. Inhaled carbogen reduces diffusion-limited tumor hypoxia, increasing tumor radiosensitivity due to the increased availability of molecular oxygen for cytotoxic radiation-induced oxygen free radical production. (NCI04) |
|---|---|
| prefLabel | Carbogen
|
| label | Carbogen
|
| PDQ_Closed_Trial_Search_ID | 42043
|
| code | C1038
|
| prefixIRI | NCIT:C1038
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| in_subset | |
| Preferred_Name | Carbogen
|
| FDA_UNII_Code | FJQ44KPA4J
|
| Contributing_Source | FDA
|
| Maps_To | Carbogen
|
| CAS_Registry | 8063-77-2
|
| NCI_Drug_Dictionary_ID | 42043
|
| Legacy Concept Name | Carbogen
|
| type | |
| ALT_DEFINITION | An inhalant of oxygen and carbon dioxide that increases the sensitivity of tumor cells to the effects of radiation therapy.
|
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 42043
|
| Accepted_Therapeutic_Use_For | inhalation therapy to produce vasodilation.
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| Semantic_Type |
Pharmacologic Substance
Inorganic Chemical
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| UMLS_CUI | C0054692
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