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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C102853
http://purl.obolibrary.org/obo/NCIT_C102853
|
|---|---|
| Preferred Name | Anti-TGF-beta RII Monoclonal Antibody IMC-TR1 |
| Definitions |
A monoclonal antibody directed against transforming growth factor-beta receptor type II (TGF-beta RII) with potential antineoplastic activity. Anti-TGF-beta RII monoclonal antibody IMC-TR1 specifically targets and binds to TGF-beta R11, thereby preventing the activation of TGF-beta RII-mediated signaling pathways. TGF-beta RII is mutated in a number of cancer cell types and is involved in cancer cell proliferation and tumor progression.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A monoclonal antibody directed against transforming growth factor-beta receptor type II (TGF-beta RII) with potential antineoplastic activity. Anti-TGF-beta RII monoclonal antibody IMC-TR1 specifically targets and binds to TGF-beta R11, thereby preventing the activation of TGF-beta RII-mediated signaling pathways. TGF-beta RII is mutated in a number of cancer cell types and is involved in cancer cell proliferation and tumor progression. |
|---|---|
| prefLabel | Anti-TGF-beta RII Monoclonal Antibody IMC-TR1
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| label | Anti-TGF-beta RII Monoclonal Antibody IMC-TR1
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| NCI_META_CUI | CL437134
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| PDQ_Closed_Trial_Search_ID | 737617
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| code | C102853
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| Has_Target | |
| prefixIRI | NCIT:C102853
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| in_subset |
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| Display_Name | Anti-TGF-beta RII Monoclonal Antibody IMC-TR1
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| Preferred_Name | Anti-TGF-beta RII Monoclonal Antibody IMC-TR1
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| Contributing_Source | CTRP
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| Maps_To | Anti-TGF-beta RII Monoclonal Antibody IMC-TR1
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| NCI_Drug_Dictionary_ID | 737617
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 737617
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| Semantic_Type | Pharmacologic Substance
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