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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C102751
http://purl.obolibrary.org/obo/NCIT_C102751
|
|---|---|
| Preferred Name | WT1 Peptide Vaccine WT2725 |
| Definitions |
A peptide cancer vaccine comprised of a peptide derived from Wilms tumor gene 1 (WT1) protein, with potential immunomodulating and antineoplastic activities. Upon administration, WT2725 may induce a specific cytotoxic T-lymphocyte (CTL) response against WT1-overexpressing tumor cells. WT1 protein, a zinc finger DNA-binding protein, is overexpressed in leukemic cells and in a vast number of non-hematological solid tumors.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A peptide cancer vaccine comprised of a peptide derived from Wilms tumor gene 1 (WT1) protein, with potential immunomodulating and antineoplastic activities. Upon administration, WT2725 may induce a specific cytotoxic T-lymphocyte (CTL) response against WT1-overexpressing tumor cells. WT1 protein, a zinc finger DNA-binding protein, is overexpressed in leukemic cells and in a vast number of non-hematological solid tumors. |
|---|---|
| prefLabel | WT1 Peptide Vaccine WT2725
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| label | WT1 Peptide Vaccine WT2725
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| NCI_META_CUI | CL437008
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| PDQ_Closed_Trial_Search_ID | 735821
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| code | C102751
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| Has_Target | |
| prefixIRI | NCIT:C102751
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| in_subset |
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| Display_Name | WT1 Peptide Vaccine WT2725
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| Preferred_Name | WT1 Peptide Vaccine WT2725
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| Contributing_Source | CTRP
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| Maps_To | WT1 Peptide Vaccine WT2725
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| NCI_Drug_Dictionary_ID | 735821
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 735821
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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