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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1025
http://purl.obolibrary.org/obo/NCIT_C1025
|
|---|---|
| Preferred Name | Bruceantin |
| Definitions |
A triterpene quassinoid antineoplastic antibiotic isolated from the plant Brucea antidysenterica. Bruceantin inhibits the peptidyl transferase elongation reaction, resulting in decreased protein and DNA synthesis. Bruceantin also has antiamoebic and antimalarial activity. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A triterpene quassinoid antineoplastic antibiotic isolated from the plant Brucea antidysenterica. Bruceantin inhibits the peptidyl transferase elongation reaction, resulting in decreased protein and DNA synthesis. Bruceantin also has antiamoebic and antimalarial activity. (NCI04) |
|---|---|
| prefLabel | Bruceantin
|
| label | Bruceantin
|
| PDQ_Closed_Trial_Search_ID | 39169
|
| code | C1025
|
| prefixIRI | NCIT:C1025
|
| in_subset | |
| Preferred_Name | Bruceantin
|
| FDA_UNII_Code | S3NW88DI4T
|
| Contributing_Source | FDA
|
| Maps_To | Bruceantin
|
| CAS_Registry | 41451-75-6
|
| NSC Number | 165563
|
| NCI_Drug_Dictionary_ID | 39169
|
| Legacy Concept Name | Bruceantin
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39169
|
| Semantic_Type |
Organic Chemical
Antibiotic
|
| UMLS_CUI | C0054160
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