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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C101794
http://purl.obolibrary.org/obo/NCIT_C101794
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|---|---|
| Preferred Name | Aerosolized Aldesleukin |
| Definitions |
An aerosol formulation of aldesleukin, a recombinant form of interleukin-2 (IL-2), with potential immunostimulating activity. Upon IL-2 inhalation, this cytokine activates lymphokine-activated killer cells and natural killer cells, and induces expression of cytotoxic cytokines, such as interferon-gamma and transforming growth factor-beta. This may eventually halt tumor cell growth. Localized administration of IL-2 may decrease toxicity and increase efficacy.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An aerosol formulation of aldesleukin, a recombinant form of interleukin-2 (IL-2), with potential immunostimulating activity. Upon IL-2 inhalation, this cytokine activates lymphokine-activated killer cells and natural killer cells, and induces expression of cytotoxic cytokines, such as interferon-gamma and transforming growth factor-beta. This may eventually halt tumor cell growth. Localized administration of IL-2 may decrease toxicity and increase efficacy. |
|---|---|
| prefLabel | Aerosolized Aldesleukin
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| label | Aerosolized Aldesleukin
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| NCI_META_CUI | CL435912
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| PDQ_Closed_Trial_Search_ID | 733682
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| code | C101794
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| Has_Target | |
| prefixIRI | NCIT:C101794
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| in_subset |
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| Display_Name | Aerosolized Aldesleukin
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| Preferred_Name | Aerosolized Aldesleukin
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| Contributing_Source | CTRP
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| Maps_To | Aerosolized Aldesleukin
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| NCI_Drug_Dictionary_ID | 733682
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 733682
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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