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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1016
http://purl.obolibrary.org/obo/NCIT_C1016
|
|---|---|
| Preferred Name | Beta-Carotene |
| Definitions |
A naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA. This agent also induces cell differentiation and apoptosis of some tumor cell types, particularly in early stages of tumorigenesis, and enhances immune system activity by stimulating the release of natural killer cells, lymphocytes, and monocytes. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA. This agent also induces cell differentiation and apoptosis of some tumor cell types, particularly in early stages of tumorigenesis, and enhances immune system activity by stimulating the release of natural killer cells, lymphocytes, and monocytes. (NCI04) |
|---|---|
| label | Beta-Carotene
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| prefLabel | Beta-Carotene
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| Legacy Concept Name | Beta_Carotene
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| in_subset | |
| Unit | mcg
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| Preferred_Name | Beta-Carotene
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| Is_Value_For_GDC_Property | |
| Chemical_Formula | C40H56
|
| USDA_ID | 321
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| Maps_To | Beta-Carotene
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| PDQ_Open_Trial_Search_ID | 40992
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| UMLS_CUI | C0053396
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| FDA_UNII_Code | 01YAE03M7J
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| prefixIRI | NCIT:C1016
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| Accepted_Therapeutic_Use_For | Dietary supplement; prevention of photosensitivity reactions in patients with erythropoietic protoporphyria; polymorphous light eruption; chemoprevention for cardiovascular disease and cancer
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| NCI_Drug_Dictionary_ID | 40992
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| INFOODS | CARTB
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| Contributing_Source |
CRCH
FDA
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| subClassOf | |
| CHEBI_ID | CHEBI:17579
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| code | C1016
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| type | |
| ALT_DEFINITION | Carotenoid consisting of a cyclic structure on each end with additional double bonds at the number 5 and 5' carbon atoms of the cyclic structures.
A substance found in yellow and orange fruits and vegetables and in dark green, leafy vegetables. The body can make vitamin A from beta carotene. Beta carotene is being studied in the prevention of some types of cancer. It is a type of antioxidant.
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| NSC Number | 62794
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| PDQ_Closed_Trial_Search_ID | 40992
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| Semantic_Type |
Pharmacologic Substance
Vitamin
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| CAS_Registry | 7235-40-7
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