Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Preferred Name	Ethyleneimine
Synonyms
Definitions	A monofunctional alkylating agent with potential antineoplastic activity. Reacting with DNA mainly at guanine and adenine residues, ethylenimine alkylates DNA, thereby producing DNA interstrand crosslinks and DNA breaks, and interfering with DNA replication and cell division. (NCI04)
ID	http://purl.obolibrary.org/obo/NCIT_C1009
CAS_Registry	151-56-4
CHEBI_ID	CHEBI:30969
Chemical_Formula	C2H5N
code	C1009
Contributing_Source	FDA
definition	A monofunctional alkylating agent with potential antineoplastic activity. Reacting with DNA mainly at guanine and adenine residues, ethylenimine alkylates DNA, thereby producing DNA interstrand crosslinks and DNA breaks, and interfering with DNA replication and cell division. (NCI04)
FDA_UNII_Code	54P5FEX9FH
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
label	Ethyleneimine
Legacy Concept Name	Ethylenimine
Maps_To	Ethyleneimine
Preferred_Name	Ethyleneimine
prefixIRI	NCIT:C1009
prefLabel	Ethyleneimine
Semantic_Type	Organic Chemical Pharmacologic Substance
UMLS_CUI	C0052794
subClassOf	http://purl.obolibrary.org/obo/NCIT_C292

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/LNC/MTHU017187	LOINC	LOOM
http://purl.bioontology.org/ontology/LNC/LP34809-1	LOINC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1009	NCIT	LOOM