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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Id | http://purl.obolibrary.org/obo/CHEBI_9649
http://purl.obolibrary.org/obo/CHEBI_9649
|
|---|---|
| Preferred Name | trandolapril |
| Definitions |
A heterobicylic compound that is (2S,3aR,7aS)-1-[(2S)-2-aminopropanoyl]octahydro-1H-indole-2-carboxylic acid in which the hydrogen of the amino group is substituted by a (2R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl group. It is a angiotensin-converting enzyme inhibitor and a prodrug used for the treatment of hypertension.
|
| Synonyms |
trandolaprilum
trandolapril
(2S,3aR,7aS)-1-((S)-N-((S)-1-carboxy-3-phenylpropyl)alanyl)hexahydro-2-indolinecarboxylic acid, 1-ethyl ester
Gopten
Mavik
Odrik
RU 44570
RU-44570
RU44570
(2S,3aR,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A heterobicylic compound that is (2S,3aR,7aS)-1-[(2S)-2-aminopropanoyl]octahydro-1H-indole-2-carboxylic acid in which the hydrogen of the amino group is substituted by a (2R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl group. It is a angiotensin-converting enzyme inhibitor and a prodrug used for the treatment of hypertension. |
|---|---|
| label |
trandolapril
|
| prefLabel |
trandolapril
|
| database_cross_reference |
PMID:8515504
Wikipedia:Trandolapril
PMID:23784370
PMID:33660934
PMID:3383998
PMID:32964020
CAS:87679-37-6
PMID:34172790
KEGG:D00383
DrugBank:DB00519
PMID:9770740
Patent:WO2006014916
PMID:25802524
Reaxys:8655766
PMID:24835355
PMID:19337528
PMID:8515501
PMID:26915813
PMID:25864194
PMID:29319234
PMID:1648489
PMID:22247843
Patent:KR20080046630
Drug_Central:2712
PMID:8515502
HMDB:HMDB0014660
PMID:27215243
PMID:8515500
PMID:8515499
Chemspider:4588590
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|
| notation |
CHEBI:9649
|
| in_subset | |
| inchi |
InChI=1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1
|
| has_related_synonym |
trandolaprilum
trandolapril
(2S,3aR,7aS)-1-((S)-N-((S)-1-carboxy-3-phenylpropyl)alanyl)hexahydro-2-indolinecarboxylic acid, 1-ethyl ester
Gopten
Mavik
Odrik
RU 44570
RU-44570
RU44570
See more
See less
|
| id |
CHEBI:9649
|
| charge |
0
|
| has_obo_namespace |
chebi_ontology
|
| formula |
C24H34N2O5
|
| subClassOf | |
| inchikey |
VXFJYXUZANRPDJ-WTNASJBWSA-N
|
| mass |
430.545
|
| monoisotopicmass |
430.24677
|
| has_functional_parent | |
| type | |
| smiles |
[H][C@@]12C[C@H](N(C(=O)[C@H](C)N[C@@H](CCC3=CC=CC=C3)C(=O)OCC)[C@@]1([H])CCCC2)C(O)=O
|
| RO_0000087 | |
| has_exact_synonym |
(2S,3aR,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid
|
| bearer of | |
| alternative term |
trandolaprilum
trandolapril
(2S,3aR,7aS)-1-((S)-N-((S)-1-carboxy-3-phenylpropyl)alanyl)hexahydro-2-indolinecarboxylic acid, 1-ethyl ester
Gopten
Mavik
Odrik
RU 44570
RU-44570
RU44570
(2S,3aR,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid
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See less
|
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