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Biological and Environmental Research Ontology
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December 23, 2022
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| Id | http://purl.obolibrary.org/obo/CHEBI_9467
http://purl.obolibrary.org/obo/CHEBI_9467
|
|---|---|
| Preferred Name | tetrabenazine |
| Definitions |
A racemate consisting of equal amounts of (3R,11bR)- and (3S,11bS)-9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one. An adrenergic uptake inhibitor, it was formerly used as an antipsychotic, but it is now used mainly for the treatment of various movement disorders including chorea, ballism, dystonias, and tardive dyskinesia.
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| Synonyms |
1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one
2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine
tetrabenazinum
1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-one
tetrabenazina
tetrabenazine
Nitoman
Ro 1-9569
TBZ
Xenazine
rac-(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
Tetrabenazine
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A racemate consisting of equal amounts of (3R,11bR)- and (3S,11bS)-9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one. An adrenergic uptake inhibitor, it was formerly used as an antipsychotic, but it is now used mainly for the treatment of various movement disorders including chorea, ballism, dystonias, and tardive dyskinesia. |
|---|---|
| label |
tetrabenazine
|
| prefLabel |
tetrabenazine
|
| database_cross_reference |
PMID:19929707
DrugBank:DB04844
KEGG:C11168
Wikipedia:Tetrabenazine
PMID:21487088
Patent:US2830993
KEGG:D08575
CAS:58-46-8
PMID:20442355
PMID:10686169
Reaxys:9356999
PMID:9040721
PMID:20869622
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|
| notation |
CHEBI:9467
|
| in_subset | |
| has_related_synonym |
1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one
2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine
tetrabenazinum
1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-one
tetrabenazina
tetrabenazine
Nitoman
Ro 1-9569
TBZ
Xenazine
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|
| id |
CHEBI:9467
|
| has part | |
| has_obo_namespace |
chebi_ontology
|
| subClassOf | |
| overlaps | |
| type | |
| RO_0000087 | |
| has_exact_synonym |
rac-(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
Tetrabenazine
|
| bearer of | |
| alternative term |
1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one
2-oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine
tetrabenazinum
1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-one
tetrabenazina
tetrabenazine
Nitoman
Ro 1-9569
TBZ
Xenazine
rac-(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
Tetrabenazine
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|
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