Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Id http://purl.obolibrary.org/obo/CHEBI_7819
http://purl.obolibrary.org/obo/CHEBI_7819
Preferred Name

oxamniquine
Definitions
A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
Synonyms
1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
(+-)-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
(+-)-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
(+-)-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
rac-oxamniquine
rac-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
oxamniquina
oxamniquine
rac-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
oxamniquinum
Mansil
UK 4271
UK-4271
UK4271
Vansil
rac-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
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Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site.
label
oxamniquine
prefLabel
oxamniquine
database_cross_reference
PMID:4977703
PMID:349665
PMID:2638729
PMID:8839672
Reaxys:485597
PMID:23450530
PMID:11516919
DrugBank:DB01096
KEGG:C07341
PMID:3127959
PMID:734715
PMID:2083150
KEGG:D00460
PMID:10321028
PDBeChem:OAQ
PMID:4203813
PMID:21500322
CAS:21738-42-1
PMID:7767464
PMID:17988075
PMID:3082231
Patent:US3821228
PMID:823880
Wikipedia:Oxamniquine
PMID:4205106
PMID:2490562
HMDB:HMDB0015228
PMID:1198006
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notation
CHEBI:7819
in_subset
has_related_synonym
1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
(+-)-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
(+-)-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
(+-)-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
rac-oxamniquine
rac-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
oxamniquina
oxamniquine
rac-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
oxamniquinum
Mansil
UK 4271
UK-4271
UK4271
Vansil
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id
CHEBI:7819
has part
charge
0
has_obo_namespace
chebi_ontology
formula
C14H21N3O3
subClassOf
overlaps
mass
279.33480
monoisotopicmass
279.15829
type
RO_0000087
has_exact_synonym
rac-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
bearer of
alternative term
1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
(+-)-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
(+-)-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
(+-)-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
rac-oxamniquine
rac-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline
oxamniquina
oxamniquine
rac-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol
oxamniquinum
Mansil
UK 4271
UK-4271
UK4271
Vansil
rac-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol
See more
See less
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