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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Id | http://purl.obolibrary.org/obo/CHEBI_75393
http://purl.obolibrary.org/obo/CHEBI_75393
|
|---|---|
| Preferred Name | Y-27632 |
| Definitions |
A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme.
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| Synonyms |
(R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide
4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide
Y 27632
trans-4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme. |
|---|---|
| label | Y-27632
|
| prefLabel | Y-27632
|
| database_cross_reference |
Reaxys:9134889
PMID:10686302
PMID:17157292
CAS:146986-50-7
PMID:17428993
Wikipedia:Y-27632
DrugBank:DB08756
PMID:17105828
PMID:10973620
See more
See less
|
| notation | CHEBI:75393
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| in_subset | |
| inchi | InChI=1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11-,12-/m1/s1
|
| has_related_synonym |
(R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide
4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide
Y 27632
|
| id | CHEBI:75393
|
| charge | 0
|
| has_obo_namespace | chebi_ontology
|
| formula | C14H21N3O
|
| subClassOf | |
| inchikey | IYOZTVGMEWJPKR-IJLUTSLNSA-N
|
| mass | 247.33600
|
| monoisotopicmass | 247.16846
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| type | |
| smiles | C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc1ccncc1
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| RO_0000087 | |
| has_exact_synonym | trans-4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide
|
| bearer of | |
| alternative term |
(R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide
4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide
Y 27632
trans-4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide
|
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